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Poly(lactic-co-glycolic) acid microspheres encapsulated in Pluronic F-127 prolong Hirudin delivery and improve functional recovery from a demyelination lesion

Components of the blood have been proposed as potential therapeutic targets for improving cellular regeneration after injury and neurodegenerative disease. In this work, thrombin is shown to increase endogenous neural progenitor proliferation in the intact murine spinal cord. A local injection of he...

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Autors principals: Sellers, Drew L., Kim, Tae Hee, Mount, Christopher W., Pun, Suzie H, Horner, Philip J.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136545/
https://ncbi.nlm.nih.gov/pubmed/25064804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.06.051
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