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Predicting the Impact of CD8(+) T Cell Polyfunctionality on HIV Disease Progression

During the chronic phase of HIV-1 infection, polyfunctional CD8(+) T cell responses, which are characterized by a high frequency of cells able to secrete multiple cytokines simultaneously, are associated with lower virus loads and slower disease progression. This relationship may arise for different...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Graw, Frederik, Regoes, Roland R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136339/
https://ncbi.nlm.nih.gov/pubmed/24965450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00647-14
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