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Modification of the Hepatitis B Virus Envelope Protein Glycosylation Pattern Interferes with Secretion of Viral Particles, Infectivity, and Susceptibility to Neutralizing Antibodies

The envelope proteins of hepatitis B virus (HBV) bear an N-linked glycosylation site at N146 within the immunodominant a-determinant in the antigenic loop (AGL) region. This glycosylation site is never fully functional, leading to a nearly 1/1 ratio of glycosylated/nonglycosylated isoforms in the vi...

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Sonraí Bibleagrafaíochta
Main Authors: Julithe, Romain, Abou-Jaoudé, Georges, Sureau, Camille
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136284/
https://ncbi.nlm.nih.gov/pubmed/24899172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01161-14
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