Crucial Roles of Interleukin-7 in the Development of T Follicular Helper Cells and in the Induction of Humoral Immunity

T follicular helper (Tfh) cells are specialized providers of cognate B cell help, which is important in promoting the induction of high-affinity antibody production in germinal centers (GCs). Interleukin-6 (IL-6) and IL-21 have been known to play important roles in Tfh cell differentiation. Here, we...

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Bibliographische Detailangaben
Hauptverfasser: Seo, Yong Bok, Im, Se Jin, Namkoong, Hong, Kim, Sae Won, Choi, Young Woo, Kang, Moon Cheol, Lim, Hye Seong, Jin, Hyun Tak, Yang, Se Hwan, Cho, Mi La, Kim, You-Me, Lee, Seung-Woo, Choi, Young Ki, Surh, Charles D., Sung, Young Chul
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136280/
https://ncbi.nlm.nih.gov/pubmed/24899182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00534-14
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