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Nucleotide Oligomerization and Binding Domain 2-Dependent Dendritic Cell Activation Is Necessary for Innate Immunity and Optimal CD8(+) T Cell Responses to Influenza A Virus Infection

Nucleotide oligomerization and binding domain (NOD)-like receptors (NLRs) are important in the innate immune response to viral infection. Recent findings have implicated NLRP3, NOD2, and NLRX1 as important players in the innate antiviral response, but their roles in the generation of adaptive immuni...

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Detalhes bibliográficos
Main Authors: Lupfer, Christopher, Thomas, Paul G., Kanneganti, Thirumala-Devi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136245/
https://ncbi.nlm.nih.gov/pubmed/24872587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01110-14
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