Exposure to Bacillus anthracis Capsule Results in Suppression of Human Monocyte-Derived Dendritic Cells

The antiphagocytic capsule of Bacillus anthracis is a major virulence factor. We hypothesized that it may also mediate virulence through inhibition of the host's immune responses. During an infection, the capsule exists attached to the bacterial surface but also free in the host tissues. We sou...

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Bibliographic Details
Main Authors: Jelacic, Tanya M., Chabot, Donald J., Bozue, Joel A., Tobery, Steven A., West, Michael W., Moody, Krishna, Yang, De, Oppenheim, Joost J., Friedlander, Arthur M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136234/
https://ncbi.nlm.nih.gov/pubmed/24891109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01857-14
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