Edwardsiella tarda-Induced Cytotoxicity Depends on Its Type III Secretion System and Flagellin

Many Gram-negative bacteria utilize a type III secretion system (T3SS) to translocate virulence proteins into host cells to cause diseases. In responding to infection, macrophages detect some of the translocated proteins to activate caspase-1-mediated cell death, called pyroptosis, and secretion of...

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Main Authors: Xie, Hai-Xia, Lu, Jin-Fang, Rolhion, Nathalie, Holden, David W., Nie, Pin, Zhou, Ying, Yu, Xiu-Jun
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2014
主題:
Molecular Pathogenesis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136207/
https://ncbi.nlm.nih.gov/pubmed/24891103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01065-13
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