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Population Pharmacokinetics and Clinical Response for Artemether-Lumefantrine in Pregnant and Nonpregnant Women with Uncomplicated Plasmodium falciparum Malaria in Tanzania

Artemether-lumefantrine (AL) is the first-line treatment for uncomplicated malaria in the second and third trimesters of pregnancy. Its efficacy during pregnancy has recently been challenged due to altered pharmacokinetic (PK) properties in this vulnerable group. The aim of this study was to determi...

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Hlavní autoři: Mosha, Dominic, Guidi, Monia, Mwingira, Felista, Abdulla, Salim, Mercier, Thomas, Decosterd, Laurent Arthur, Csajka, Chantal, Genton, Blaise
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136066/
https://ncbi.nlm.nih.gov/pubmed/24867986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02595-14
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