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Alternative Strategies for Proof-of-Principle Studies of Antibacterial Agents

The proof that a new antibacterial agent is not only active in vitro but also effective in vivo under clinically relevant conditions is currently provided (i) by using appropriate nonclinical models of infection and pharmacokinetic-pharmacodynamic (PK-PD) analysis providing evidence of the likelihoo...

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Detalhes bibliográficos
Main Authors: Dalhoff, Axel, Weintraub, Andrej, Nord, Carl Erik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136043/
https://ncbi.nlm.nih.gov/pubmed/24867989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02473-14
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