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Extended-Infusion versus Standard-Infusion Piperacillin-Tazobactam for Sepsis Syndromes at a Tertiary Medical Center

Piperacillin-tazobactam (PTZ) is frequently used as empirical and targeted therapy for Gram-negative sepsis. Time-dependent killing properties of PTZ support the use of extended-infusion (EI) dosing; however, studies have shown inconsistent benefits of EI PTZ treatment on clinical outcomes. We perfo...

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Bibliographic Details
Main Authors: Cutro, Scott R., Holzman, Robert, Dubrovskaya, Yanina, Chen, Xian Jie Cindy, Ahuja, Tania, Scipione, Marco R., Chen, Donald, Papadopoulos, John, Phillips, Michael S., Mehta, Sapna A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Clinical Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136013/
https://ncbi.nlm.nih.gov/pubmed/24867975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02759-14
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