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Intravitreal Injection of the Chimeric Phage Endolysin Ply187 Protects Mice from Staphylococcus aureus Endophthalmitis

The treatment of endophthalmitis is becoming very challenging due to the emergence of multidrug-resistant bacteria. Hence, the development of novel therapeutic alternatives for ocular use is essential. Here, we evaluated the therapeutic potential of Ply187AN-KSH3b, a chimeric phage endolysin derived...

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Detalhes bibliográficos
Main Authors: Singh, Pawan Kumar, Donovan, David M., Kumar, Ashok
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136012/
https://ncbi.nlm.nih.gov/pubmed/24890598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00126-14
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