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Evaluation of the Contributions of Individual Viral Genes to Newcastle Disease Virus Virulence and Pathogenesis

Naturally occurring Newcastle disease virus (NDV) strains vary greatly in virulence. The presence of multibasic residues at the proteolytic cleavage site of the fusion (F) protein has been shown to be a primary determinant differentiating virulent versus avirulent strains. However, there is wide var...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Paldurai, Anandan, Kim, Shin-Hee, Nayak, Baibaswata, Xiao, Sa, Shive, Heather, Collins, Peter L., Samal, Siba K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135945/
https://ncbi.nlm.nih.gov/pubmed/24850737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00666-14
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