Interaction between Hantavirus Nucleocapsid Protein (N) and RNA-Dependent RNA Polymerase (RdRp) Mutants Reveals the Requirement of an N-RdRp Interaction for Viral RNA Synthesis

Viral ribonucleocapsids harboring the viral genomic RNA are used as the template for viral mRNA synthesis and replication of the viral genome by viral RNA-dependent RNA polymerase (RdRp). Here we show that hantavirus nucleocapsid protein (N protein) interacts with RdRp in virus-infected cells. We ma...

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Hlavní autoři: Cheng, Erdong, Wang, Zekun, Mir, Mohammad A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135928/
https://ncbi.nlm.nih.gov/pubmed/24850733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00405-14
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