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The next generation of sepsis trials: What’s next after the demise of recombinant human activated Protein C?

Progress in the development of novel therapeutics to treat sepsis has come to virtual standstill. While enormous strides have been made in the understanding of basic molecular mechanisms that underlie the pathophysiology of sepsis, a distressingly long list of novel therapeutic agents have been test...

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Detalhes bibliográficos
Main Authors: Opal, Steven M., Dellinger, R. Phillip, Vincent, Jean-Louis, Masur, Henry, Angus, Derek C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135726/
https://ncbi.nlm.nih.gov/pubmed/24717456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000000325
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