The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion.

Ras GTPase activating protein (GAP) possesses a C-terminal domain that interacts with GTP-bound Ras, and an N-terminal region containing two SH2 domains and an SH3 domain. In addition to its association with Ras, GAP binds stably to autophosphorylated beta PDGF receptors, and to two cytoplasmic phos...

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Detalhes bibliográficos
Main Authors: McGlade, J, Brunkhorst, B, Anderson, D, Mbamalu, G, Settleman, J, Dedhar, S, Rozakis-Adcock, M, Chen, L B, Pawson, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC413572/
https://ncbi.nlm.nih.gov/pubmed/8344248
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