Maternal Pre-Gravid Obesity Changes Gene Expression Profiles Towards Greater Inflammation and Reduced Insulin Sensitivity in Umbilical Cord

BACKGROUND: Maternal obesity is associated with unfavorable outcomes, which may be reflected in the as yet undiscovered gene expression profiles of the umbilical cord (UC). METHODS: UCs from 12 lean (pre-gravid BMI < 24.9) and 10 overweight/obese (OW/OB, pre-gravid BMI ≥25) women without gestatio...

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Main Authors: Thakali, Keshari M., Saben, Jessica, Faske, Jennifer B., Lindsey, Forrest, Gomez-Acevedo, Horacio, Lowery, Curtis L., Badger, Thomas M., Andres, Aline, Shankar, Kartik
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135718/
https://ncbi.nlm.nih.gov/pubmed/24819376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2014.72
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