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Identification of a Unique Radical S-Adenosylmethionine Methylase Likely Involved in Methanopterin Biosynthesis in Methanocaldococcus jannaschii

Methanopterin (MPT) and its analogs are coenzymes required for methanogenesis and methylotrophy in specialized microorganisms. The methyl groups at C-7 and C-9 of the pterin ring distinguish MPT from all other pterin-containing natural products. However, the enzyme(s) responsible for the addition of...

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Autores principales: Allen, Kylie D., Xu, Huimin, White, Robert H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135684/
https://ncbi.nlm.nih.gov/pubmed/25002541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01903-14
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