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Benzylidene Acylhydrazides Inhibit Chlamydial Growth in a Type III Secretion- and Iron Chelation-Independent Manner

Chlamydiae are widespread Gram-negative pathogens of humans and animals. Salicylidene acylhydrazides, developed as inhibitors of type III secretion system (T3SS) in Yersinia spp., have an inhibitory effect on chlamydial infection. However, these inhibitors also have the capacity to chelate iron, and...

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Detalhes bibliográficos
Main Authors: Bao, Xiaofeng, Gylfe, Åsa, Sturdevant, Gail L., Gong, Zheng, Xu, Shuang, Caldwell, Harlan D., Elofsson, Mikael, Fan, Huizhou
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135636/
https://ncbi.nlm.nih.gov/pubmed/24914180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01677-14
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