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Nrf2- and ATF4-Dependent Upregulation of xCT Modulates the Sensitivity of T24 Bladder Carcinoma Cells to Proteasome Inhibition

The ubiquitin-proteasome pathway degrades ubiquitinated proteins to remove damaged or misfolded protein and thus plays an important role in the maintenance of many important cellular processes. Because the pathway is also crucial for tumor cell growth and survival, proteasome inhibition by specific...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ye, Peng, Mimura, Junsei, Okada, Tomomi, Sato, Hideyo, Liu, Tao, Maruyama, Atsushi, Ohyama, Chikara, Itoh, Ken
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135628/
https://ncbi.nlm.nih.gov/pubmed/25002527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00221-14
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