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RORα Binds to E2F1 To Inhibit Cell Proliferation and Regulate Mammary Gland Branching Morphogenesis

Retinoic acid receptor-related orphan nuclear receptor alpha (RORα) is a potent tumor suppressor that reduces cell proliferation and inhibits tumor growth. However, the molecular mechanism by which it inhibits cell proliferation remains unknown. We demonstrate a noncanonical nuclear receptor pathway...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xiong, Gaofeng, Xu, Ren
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135605/
https://ncbi.nlm.nih.gov/pubmed/24891616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00279-14
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