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Direct Transcriptional Repression of Zfp423 by Zfp521 Mediates a Bone Morphogenic Protein-Dependent Osteoblast versus Adipocyte Lineage Commitment Switch

Osteoblasts and adipocytes arise from a common mesenchymal precursor cell. The cell fate decision of a mesenchymal precursor cell is under the influence of molecular cues and signaling pathways that lead to the activation or repression of lineage-specific transcription factors. The molecular mechani...

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Autori principali: Addison, William N., Fu, Martin M., Yang, Helen X., Lin, Zhao, Nagano, Kenichi, Gori, Francesca, Baron, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135594/
https://ncbi.nlm.nih.gov/pubmed/24891617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00185-14
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