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Mutations on the DNA Binding Surface of TBP Discriminate between Yeast TATA and TATA-Less Gene Transcription

Most RNA polymerase (Pol) II promoters lack a TATA element, yet nearly all Pol II transcription requires TATA binding protein (TBP). While the TBP-TATA interaction is critical for transcription at TATA-containing promoters, it has been unclear whether TBP sequence-specific DNA contacts are required...

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Hlavní autoři: Kamenova, Ivanka, Warfield, Linda, Hahn, Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135567/
https://ncbi.nlm.nih.gov/pubmed/24865972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01685-13
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