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Conformational Analysis of a Dermatan Sulfate-Derived Tetrasaccharide by NMR, Molecular Modeling, and Residual Dipolar Couplings

The solution conformation behavior of a dermatan-derived tetrasaccharide—ΔHexA-(1→3)-GalNAc4S-β-(1→4)-IdoA-α-(1→3)-red-GalNAc4S (S is a sulfate group)—has been explored by means of NMR spectroscopy, especially by NOE-based conformational analysis. The tetrasaccharide was present as four species, two...

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Autori principali: Silipo, Alba, Zhang, Zhenqing, Cañada, F. Javier, Molinaro, Antonio, Linhardt, Robert J., Jiménez-Barbero, Jesús
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135520/
https://ncbi.nlm.nih.gov/pubmed/18072186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200700400
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