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Asymmetrical recognition and activity of the I-SceI endonuclease on its site and on intron-exon junctions.

Group I intron-encoded endonucleases represent a new class of double strand cutting endonucleases whose function is to initiate the homing of introns by generating double strand breaks in site-specific sequences. We have studied the mechanism of interaction of the I-SceI endonuclease with different...

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Bibliographic Details
Published in:EMBO J
Main Authors: Perrin, A, Buckle, M, Dujon, B
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413549/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8335007/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05956.x
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