Thrombospondin related anonymous protein (TRAP) of Plasmodium falciparum binds specifically to sulfated glycoconjugates and to HepG2 hepatoma cells suggesting a role for this molecule in sporozoite invasion of hepatocytes.

Thrombospondin related anonymous protein (TRAP) of Plasmodium falciparum contains an amino acid motif based around the sequence WSPCSVTCG which is also found in region II of the circumsporozoite (CS) proteins of different species of Plasmodium. This amino acid motif confers on the CS protein the abi...

Full description

Bibliographic Details

Published in:	EMBO J
Main Authors:	Müller, H M, Reckmann, I, Hollingdale, M R, Bujard, H, Robson, K J, Crisanti, A
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 1993
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8392935/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05950.x
Tags:	Add Tag No Tags, Be the first to tag this record!