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Heterogeneity in glucose sensitivity among pancreatic beta-cells is correlated to differences in glucose phosphorylation rather than glucose transport.

Rat beta-cells differ in their individual rates of glucose-induced insulin biosynthesis and release. This functional heterogeneity has been correlated with intercellular differences in metabolic redox responsiveness to glucose. The present study compares glucose metabolism in two beta-cell subpopula...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Heimberg, H, De Vos, A, Vandercammen, A, Van Schaftingen, E, Pipeleers, D, Schuit, F
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413540/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8335003/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05949.x
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