Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells.

Chronic myelogenous leukemia evolves in two clinically distinct stages: a chronic and a blast crisis phase. The molecular changes associated with chronic phase to blast crisis transition are largely unknown. We have identified a cDNA clone, DR-nm23, differentially expressed in a blast-crisis cDNA li...

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Bibliographic Details
Main Authors: Venturelli, D, Martinez, R, Melotti, P, Casella, I, Peschle, C, Cucco, C, Spampinato, G, Darzynkiewicz, Z, Calabretta, B
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC41354/
https://ncbi.nlm.nih.gov/pubmed/7638209
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