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Two rare variations, D478N and D478E, that occur at the same amino acid residue in nicotinic acetylcholine receptor (nAChR) α2 subunit influence nAChR function

There occur two rare variations, Asp(D)478Asn(N) and Asp(D)478Glu(E), in the putative cytoplasmic amphipathic α-helices of human nicotinic acetylcholine receptor (nAChR) α2 subunit as a result of mutation in the 1(st) (G→A: rs141072985) and 3(rd) (C→A: rs56344740) nucleotide of its 478(th) triplet c...

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Bibliographische Detailangaben
Hauptverfasser: Dash, Bhagirathi, Li, Ming D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135378/
https://ncbi.nlm.nih.gov/pubmed/24950454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.05.014
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