THE INNATE IMMUNE RESPONSE AND ACTIVATION OF COAGULATION IN α1,3-GALACTOSYLTRANSFERASE GENE-KNOCKOUT XENOGRAFT RECIPIENTS

BACKGROUND: The role of the innate immune system in the development of thrombotic microangiopathy (TM) after α1,3-galactosyltransferase gene-knockout (GTKO) pig organ transplantation in primates is uncertain. METHODS: Twelve organs (9 hearts, 3 kidneys) from GTKO pigs were transplanted into baboons...

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Main Authors: Ezzelarab, Mohamed, Garcia, Bertha, Azimzadeh, Agnes, Sun, Hongtao, Lin, Chih Che, Hara, Hidetaka, Kelishadi, Sean, Zhang, Tianshu., Lin, Yih Jyh, Tai, Hao-Chi, Wagner, Robert, Thacker, Jnanesh, Murase, Noriko, McCurry, Kenneth, Barth, Rolf N., Ayares, David, Pierson, Richard N., Cooper, David KC.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135362/
https://ncbi.nlm.nih.gov/pubmed/19300181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e318199c34f
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