Conserved transducer coupling but different effector linkage upon expression of the myeloid fMet-Leu-Phe receptor in insulin secreting cells.

In neutrophils fMet-Leu-Phe activates phospholipase C via a pertussis toxin sensitive G-protein and induces granule secretion. We have transfected a human cDNA sequence encoding the fMet-Leu-Phe receptor into the insulin secreting cell line RINm5F to study receptor-effector coupling with special reg...

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Bibliografische Detailangaben

Veröffentlicht in:	EMBO J
Hauptverfasser:	Lang, J, Boulay, F, Li, G, Wollheim, C B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413515/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8392932/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05928.x
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