NAG-1/GDF15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism

OBJECTIVE: Obesity is a major health problem associated with high morbidity and mortality. NSAID activated gene, (NAG-1) is a TGF-β superfamily member reported to alter adipose tissue levels in mice. We investigated whether hNAG-1 acts as a regulator of adiposity and energy metabolism. DESIGN/SUBJEC...

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Main Authors: Chrysovergis, Kali, Wang, Xingya, Kosak, Justin, Lee, Seong-Ho, Kim, Jong Sik, Foley, Julie F., Travlos, Greg, Singh, Shubha, Baek, Seung Joon, Eling, Thomas E.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135041/
https://ncbi.nlm.nih.gov/pubmed/24531647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2014.27
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