A Family of Excitatory Peptide Toxins from Venomous Crassispirine Snails: Using Constellation Pharmacology to Assess Bioactivity

The toxinology of the crassispirine snails, a major group of venomous marine gastropods within the superfamily Conoidea, is largely unknown. Here we define the first venom peptide superfamily, the P-like crassipeptides, and show that the organization of their gene sequences is similar to conotoxin p...

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Hauptverfasser: Imperial, Julita S., Cabang, April B., Song, Jie, Raghuraman, Shrinivasan, Gajewiak, Joanna, Watkins, Maren, Showers-Corneli, Patrice, Fedosov, Alexander, Concepcion, Gisela P., Terlau, Heinrich, Teichert, Russell W., Olivera, Baldomero M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134995/
https://ncbi.nlm.nih.gov/pubmed/24997406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2014.06.014
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