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Generation of effector cells that localize to mucosal tissues and form resident memory CD8 T cells is controlled by mTOR

Mucosal tissues are subject to frequent pathogen exposure and major sites for transmission of infectious disease. CD8 T cells play a critical role in controlling mucosa-acquired infections though their migration into mucosal tissues is tightly regulated. The mechanisms and signals that control the f...

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Detalhes bibliográficos
Main Authors: Sowell, Ryan T., Rogozinska, Magdalena, Nelson, Christine E., Vezys, Vaiva, Marzo, Amanda L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134982/
https://ncbi.nlm.nih.gov/pubmed/25070853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400074
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