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Genome Rearrangement of Influenza Virus for Anti-Viral Drug Screening

Rearrangement of the influenza A genome such that NS2 is expressed downstream of PB1 permits the insertion of a foreign gene in the NS gene segment. In this report, the genome rearranged strategy was extended to A/California/04/2009 (pH1N1), and Gaussia luciferase (GLuc) or GFP was expressed downstr...

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Detalhes bibliográficos
Main Authors: Sutton, Troy C., Obadan, Adebimpe, Lavigne, Johanna, Chen, Hongjun, Li, Weizhong, Perez, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134972/
https://ncbi.nlm.nih.gov/pubmed/24833536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2014.05.003
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