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Geminin loss causes neural tube defects through disrupted progenitor specification and neuronal differentiation
Geminin is a nucleoprotein that can directly bind chromatin regulatory complexes to modulate gene expression during development. Geminin knockout mouse embryos are preimplantation lethal by the 32-cell stage, precluding in vivo study of Geminin's role in neural development. Therefore, here we u...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134736/ https://ncbi.nlm.nih.gov/pubmed/24995796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.06.021 |
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