L-leucine, beta-hydroxy-beta-methylbutyric acid (HMB) and creatine monohydrate prevent myostatin-induced Akirin-1/Mighty mRNA down-regulation and myotube atrophy

BACKGROUND: The purpose of this study was to examine if L-leucine (Leu), β-hydroxy-β-methylbutyrate (HMB), or creatine monohydrate (Crea) prevented potential atrophic effects of myostatin (MSTN) on differentiated C2C12 myotubes. METHODS: After four days of differentiation, myotubes were treated with...

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Main Authors: Mobley, Christopher Brooks, Fox, Carlton D, Ferguson, Brian S, Amin, Rajesh H, Dalbo, Vincent J, Baier, Shawn, Rathmacher, John A, Wilson, Jacob M, Roberts, Michael D
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134516/
https://ncbi.nlm.nih.gov/pubmed/25132809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1550-2783-11-38
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