DNA methylation status is more reliable than gene expression at detecting cancer in prostate biopsy

BACKGROUND: We analysed critically the potential usefulness of RNA- and DNA-based biomarkers in supporting conventional histological diagnostic tests for prostate carcinoma (PCa) detection. METHODS: Microarray profiling of gene expression and DNA methylation was performed on 16 benign prostatic hype...

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Autori principali: Paziewska, A, Dabrowska, M, Goryca, K, Antoniewicz, A, Dobruch, J, Mikula, M, Jarosz, D, Zapala, L, Borowka, A, Ostrowski, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134497/
https://ncbi.nlm.nih.gov/pubmed/24937670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.337
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