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Downregulation of Microvascular Endothelial Type B Endothelin Receptor is a Central Vascular Mechanism in Hypertensive Pregnancy

Preeclampsia is a pregnancy-related disorder characterized by hypertension (HTN) with unclear mechanism. Studies have shown endothelial dysfunction and increased endothelin-1 (ET-1) levels in hypertensive-pregnancy (HTN-Preg). ET-1 activates endothelin receptor type-A (ET(A)R) in vascular smooth mus...

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Hlavní autoři: Mazzuca, Marc Q., Li, Wei, Reslan, Ossama M., Yu, Peng, Mata, Karina M., Khalil, Raouf A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134432/
https://ncbi.nlm.nih.gov/pubmed/24914193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03315
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