A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole.

The Vps15 protein kinase and the Vps34 phosphatidylinositol 3-kinase (PI 3-kinase) are required for the sorting of soluble hydrolases to the yeast vacuole. Over-production of Vps34p suppresses the growth and vacuolar protein sorting defects associated with vps15 kinase domain mutants, suggesting tha...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	EMBO J
Autori principali:	Stack, J H, Herman, P K, Schu, P V, Emr, S D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8387919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05867.x
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!