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Impact of methionine oxidation as an initial event on the pathway of human prion protein conversion
Prion diseases comprise a group of fatal neurodegenerative disorders characterized by the autocatalytic conversion of the cellular prion protein PrP(C) into the infectious misfolded isoform PrP(Sc). Increasing evidence supports a specific role of oxidative stress in the onset of pathogenesis. Althou...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134345/ https://ncbi.nlm.nih.gov/pubmed/24121542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.26745 |
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