Oligosaccharide Substrate Preferences of Human Extracellular Sulfatase Sulf2 Using Liquid Chromatography-Mass Spectrometry Based Glycomics Approaches

Sulfs are extracellular endosulfatases that selectively remove the 6-O-sulfate groups from cell surface heparan sulfate (HS) chain. By altering the sulfation at these particular sites, Sulfs function to remodel HS chains. As a result of the remodeling activity, HSulf2 regulates a multitude of cell-s...

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Bibliographic Details
Main Authors: Huang, Yu, Mao, Yang, Buczek-Thomas, Jo Ann, Nugent, Matthew A., Zaia, Joseph
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134258/
https://ncbi.nlm.nih.gov/pubmed/25127119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105143
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