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The X Gene of Adeno-Associated Virus 2 (AAV2) Is Involved in Viral DNA Replication

Adeno-associated virus (AAV) (type 2) is a popular human gene therapy vector with a long active transgene expression period and no reported vector-induced adverse reactions. Yet the basic molecular biology of this virus has not been fully addressed. One potential gene at the far 3′ end of the AAV2 g...

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Bibliographische Detailangaben
Hauptverfasser: Cao, Maohua, You, Hong, Hermonat, Paul L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134208/
https://ncbi.nlm.nih.gov/pubmed/25127256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104596
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