Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast.

It is widely assumed that degradation of mitotic cyclins causes a decrease in mitotic cdc2/CDC28 kinase activity and thereby triggers the metaphase to anaphase transition. Two observations made on the budding yeast Saccharomyces cerevisiae are inconsistent with this scenario: (i) anaphase occurs in...

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Bibliografische Detailangaben

Veröffentlicht in:	EMBO J
Hauptverfasser:	Surana, U, Amon, A, Dowzer, C, McGrew, J, Byers, B, Nasmyth, K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8491189/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05846.x
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