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Characterization of full-length neurofibromin: tubulin inhibits Ras GAP activity.

Full-length neurofibromin is a GTPase activating protein (GAP) for the Ras proto-oncogene product. Regulation of neurofibromin activity therefore has important implications for cell growth. Neurofibromin co-purifies with tubulin when expressed in insect cells. The interaction between neurofibromin a...

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Bibliografiske detaljer
Main Authors: Bollag, G, McCormick, F, Clark, R
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC413413/
https://ncbi.nlm.nih.gov/pubmed/8491185
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