Global transcriptome-wide analysis of CIK cells identify distinct roles of IL-2 and IL-15 in acquisition of cytotoxic capacity against tumor

BACKGROUND: Cytokine-induced killer (CIK) cells are an emerging approach of cancer treatment. Our previous study have shown that CIK cells stimulated with combination of IL-2 and IL-15 displayed improved proliferation capacity and tumor cytotoxicity. However, the mechanisms of CIK cell proliferation...

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Bibliografische gegevens
Hoofdauteurs: Wang, Wenju, Meng, Mingyao, Zhang, Yayong, Wei, Chuanyu, Xie, Yanhua, Jiang, Lihong, Wang, Chunhui, Yang, Fang, Tang, Weiwei, Jin, Xingfang, Chen, Dai, Zong, Jie, Hou, Zongliu, Li, Ruhong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134122/
https://ncbi.nlm.nih.gov/pubmed/25108500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-7-49
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