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The influence of bile salt on the chemotherapeutic response of docetaxel-loaded thermosensitive nanomicelles

The primary aim of this work was to investigate the potential of bile salt, sodium taurocholate (NaTC), in improving the bioavailability and anti-tumor efficacy of docetaxel (DCT) upon rectal administration. Poloxamer-based nanomicelles with thermosensitive and mucoadhesive properties were prepared...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Dong Wuk, Ramasamy, Thiruganesh, Choi, Ju Yeon, Kim, Jeong Hwan, Yong, Chul Soon, Kim, Jong Oh, Choi, Han-Gon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134046/
https://ncbi.nlm.nih.gov/pubmed/25143730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S64794
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