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Target-directed development and preclinical characterization of the proposed biosimilar rituximab GP2013

Biosimilar development involves a target-directed iterative process to ensure a similar product to the originator. Here we report the preclinical development of the proposed biosimilar rituximab (GP2013). Post-translational modifications and bioactivities of GP2013 versus originator rituximab were e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: da Silva, Antonio, Kronthaler, Ulrich, Koppenburg, Vera, Fink, Martin, Meyer, Ines, Papandrikopoulou, Anastassia, Hofmann, Matthias, Stangler, Thomas, Visser, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Informa Healthcare 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133973/
https://ncbi.nlm.nih.gov/pubmed/24024472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2013.843090
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