Modification and inactivation of Cu,Zn-superoxide dismutase by the lipid peroxidation product, acrolein

Acrolein is the most reactive aldehydic product of lipid peroxidation and is found to be elevated in the brain when oxidative stress is high. The effects of acrolein on the structure and function of human Cu,Zn-superoxide dismutase (SOD) were examined. When Cu,Zn-SOD was incubated with acrolein, the...

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Bibliographic Details
Main Author: Kang, Jung Hoon
Format: Artigo
Language:Inglês
Published: Korean Society for Biochemistry and Molecular Biology 2013
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133839/
https://ncbi.nlm.nih.gov/pubmed/24152914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.11.138
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