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Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells

Occludin is the first identified protein in the tight junction (TJ), but its function has remained for the most part obscure. TJs have been demonstrated to play important roles in the inner ear function, and occludin is expressed in all the epithelial TJs in the inner ear. Thus, we examined the inne...

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Autors principals: Kitajiri, Shin-ichiro, Katsuno, Tatsuya, Sasaki, Hiroyuki, Ito, Juichi, Furuse, Mikio, Tsukita, Shoichiro
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133728/
https://ncbi.nlm.nih.gov/pubmed/25063198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20147799
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