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ReformAlign: improved multiple sequence alignments using a profile-based meta-alignment approach

BACKGROUND: Obtaining an accurate sequence alignment is fundamental for consistently analyzing biological data. Although this problem may be efficiently solved when only two sequences are considered, the exact inference of the optimal alignment easily gets computationally intractable for the multipl...

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Autori principali: Lyras, Dimitrios P, Metzler, Dirk
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133627/
https://ncbi.nlm.nih.gov/pubmed/25099134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-265
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