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ReformAlign: improved multiple sequence alignments using a profile-based meta-alignment approach

BACKGROUND: Obtaining an accurate sequence alignment is fundamental for consistently analyzing biological data. Although this problem may be efficiently solved when only two sequences are considered, the exact inference of the optimal alignment easily gets computationally intractable for the multipl...

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Detalles Bibliográficos
Main Authors: Lyras, Dimitrios P, Metzler, Dirk
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133627/
https://ncbi.nlm.nih.gov/pubmed/25099134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-265
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